Maurice Watson Jr. scored 21 points and No. 8 Creighton matched its best start in program history with a 75-64 victory over No. 12 Butler on Wednesday night.
The Bluejays (16-1, 4-2 Big East) rode hot shooting in the first half to build a big lead that Butler (14-3, 3-2) couldn't overcome with its star Kelan Martin still struggling with his shot.
Watson made 9 of 14 shots and had seven assists but committed a season-high eight turnovers. Khyri Thomas added 14 points and 12 rebounds, and Cole Huff and Justin Patton each had 10 points.
Avery Woodson led the Bulldogs with 14 points.
Butler lost for the first time in five games against Top 25 opponents, and it failed in the bid for a fourth win over a top 10 opponent. All of the losses have come on the road.